Increased mortality persists in drug-resistant epilepsy

From Clinical Neurology News, 24 February 2014: Drug-resistant epilepsy is associated with a significant increase in mortality that persists for decades after diagnosis, particularly among individuals with a known etiology, according to data from a retrospective, multicenter cohort study. Dr. Brian Callaghan of the University of Michigan, Ann Arbor, and his colleagues identified 433 patients Continue reading Increased mortality persists in drug-resistant epilepsy

Postsurgical withdrawal of antiepileptic drugs raises only short-term seizure risk

From Clinical Neurology News, 24 February 2014: Withdrawing antiepileptic medication after temporal lobe epilepsy surgery may increase the risk of breakthrough seizures in the short term but does not alter long-term remission rates, a retrospective, observational cohort study found. Two years after surgery, 69% of patients whose medication was discontinued at 1 year were completely Continue reading Postsurgical withdrawal of antiepileptic drugs raises only short-term seizure risk

Stem cell transplantation effective in aggressive relapsing-remitting MS

From Clinical Neurology News, 27 February 2014: Autologous hematopoietic stem cell transplantation was an effective treatment option for aggressive multiple sclerosis, particularly in patients with inflammatory activity at baseline, in a study of the Swedish experience with the procedure since it was first performed there in 2004. A prospective, observational study of 41 patients with Continue reading Stem cell transplantation effective in aggressive relapsing-remitting MS

COPD may boost risk of cerebral microbleeds

From Clinical Neurology News, 19 July 2013: Chronic obstructive pulmonary disease was associated with an increased risk of cerebral microbleeds – a marker of cerebral small vessel disease – independent of factors such as age, sex, smoking status, and cholesterol levels, according to a prospective, population-based cohort study. “Depression, postural instability, cognitive and functional impairment Continue reading COPD may boost risk of cerebral microbleeds