From Clinical Neur0logy News, 21 June 2013:
Patients with mild cognitive impairment in Parkinson’s disease often show memory impairment and problems with visuospatial function, attention, and executive function, according to a study attempting to characterize the condition.
A cohort study assessed 219 patients newly diagnosed with Parkinson’s disease but without dementia and 99 age-matched controls using new criteria for the diagnosis of mild cognitive impairment in Parkinson’s disease (PD-MCI).
The criteria, released last year by the Movement Disorder Society, include tests of global cognition, attention, memory, executive function, visuospatial function, and language (Mov. Disord. 2012;27:349-56).
Patients were classified as having level 1 MCI if they scored less than 26 out of 30 on the Montreal Cognitive Assessment (MoCA), and as level 2 MCI if they were impaired on two tests in one cognitive domain or one impaired test in two different domains at 1, 1.5, or 2 standard deviations (SD) below normative values.
According to data presented in the Junior Award session at the international congress of Parkinson’s Disease and Movement Disorders, 41.5% of participants met the criteria for level 1 PD-MCI, while 65.8% met level 2 criteria at 1 SD below normative values, 42.5% at 1.5 SD, and 22.4% at 2 SD below norm.
The study found that among participants at 1.5 SD below normative values, memory impairment was the most common deficit (15.1%), followed by visuospatial (13.2%), attention (12.3%), and then executive dysfunction (11%). Read more.