Severe hydroxychloroquine non-adherence linked to worse SLE outcomes

From Rheumatology News, 25 May 2023: Regular testing of hydroxychloroquine levels in patients with systemic lupus erythematosus – especially those who are experiencing a disease flare – could help to identify patients who are not taking their treatment and are at risk of worse outcomes. Data presented at an international congress on systemic lupus erythematosus … Continue reading Severe hydroxychloroquine non-adherence linked to worse SLE outcomes

Patient selection key to lowering placebo response rates in lupus clinical trials

From Rheumatology News, 13 June 2023: A major challenge for clinical trials in systemic lupus erythematosus (SLE) is how to get the placebo response rate down low enough that the effectiveness of a drug can actually be seen. Better patient selection may be the key. Speaking at an international congress on SLE, Joan Merrill, MD, … Continue reading Patient selection key to lowering placebo response rates in lupus clinical trials