Tag: lupus

Severe hydroxychloroquine non-adherence linked to worse SLE outcomes

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From Rheumatology News, 25 May 2023: Regular testing of hydroxychloroquine levels in patients with systemic lupus erythematosus – especially those who are experiencing a disease flare – could help to identify patients who are not taking their treatment and are at risk of worse outcomes. Data presented at an international congress on systemic lupus erythematosus … Continue reading Severe hydroxychloroquine non-adherence linked to worse SLE outcomes

Patient selection key to lowering placebo response rates in lupus clinical trials

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From Rheumatology News, 13 June 2023: A major challenge for clinical trials in systemic lupus erythematosus (SLE) is how to get the placebo response rate down low enough that the effectiveness of a drug can actually be seen. Better patient selection may be the key. Speaking at an international congress on SLE, Joan Merrill, MD, … Continue reading Patient selection key to lowering placebo response rates in lupus clinical trials

Strategies for complete B-cell depletion evolve for patients with lupus nephritis

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From Rheumatology News, 13 June 2023: B cell–depleting therapies in patients with lupus nephritis have a higher likelihood of complete response if B cells are almost completely depleted, and strategies for achieving more complete B-cell depletion continue to be tested, according to evidence presented by Richard A. Furie, MD, at an international congress on systemic … Continue reading Strategies for complete B-cell depletion evolve for patients with lupus nephritis